Clinical Application of Chinese Herbal Injection for Cancer Care: Evidence-Mapping of the Systematic Reviews, Meta-analyses, and Randomized Controlled Trials

Background and objective: Cancer is a life-threatening disease worldwide current standard therapy cannot fulfill all clinical needs. Chinese herbal injections have been widely used for cancer in Western hospitals China. This study aimed to apply evidence mapping order provide an overview of the application care based on randomized controlled trials, systematic reviews, meta-analyses. Methods results: Seven databases were systematically searched eligible meta-analyses ten treatment covered national essential health insurance program. Excel 2016 RStudio integrate process data. In total 366 trials 48 reviews included medicines including; Compound Kushen, Shenqi Fuzheng, Aidi, Kangai, Kanglaite, Xiaoaiping, Cinobufacin, Brucea javanica oil emulsion, Polyporus polysaccharide injection, Astragalus injection. Health restricts scope these injections. The numbers studies published increased, especially around 2013–2015. most studied types lung (118, 32.2%), colorectal (39, 10.7%), gastric Kushen (78, 21.3%), Fuzheng (76, 20.8%), Aidi (63, 17.2%). consistently reported benefits observed Kangai tumor response, quality life, myelosuppression, enhancing immunity. Conclusion: provides outcomes effects care, offers information their which warrants further evidence-based research inform policy decision-making.